An important study published on 5th December 2016 in Nature Medicine, reported that depression can be divided into subtypes ( biotypes) on the basis of abnormal connectivity in limbic and frontostraital networks of the brain by using functional MRI( fMRI).
This was a large multi centre study ( 1188). These biotypes cannot be differentiated solely on the basis of clinical features, but they are associated with differing clinical-symptom profiles.
Clustering patients on this basis enabled the development of diagnostic biomarkers with high (82–93%) sensitivity and specificity for depression subtypes in multisite validation and out-of-sample replication data sets.They also predict responsiveness to transcranial-magnetic-stimulation therapy.
The study reported that these four biotypes of depression varied not only in their clinical symptoms but also their response to transcranial magnetic stimulation therapy.
News in less than 200 words
Here we will update you with most important research or news related to mental health in less than 200 words. This page was started in December 2016.